王德恒 研究员 硕导
王德恒 研究员 硕导
王德恒 Ph.D 研究员,神经科学在体电生理学实验室负责人,上海中医药大学杏林学者。
电子邮箱(E-mail): wangdeheng (at) shutcm.edu.cn
办公室电话:021-51323172
一、研究方向
1. 脑机接口
2. 癫痫、老年性神经退行性疾病的神经信息编码
3. 基因、药物对大脑编码的影响
二、发表论文(Selected Publications)
1. Hong Ni*, Zhongzhao Guo*, Yue Wu, Jie Wang, Zilu Zhu, Deheng Wang#. The Crucial Role of Hippocampus Cyclooxygenase-2 Plays in Synaptic Plasticity and Memory, European Journal of Neuroscience, 2023 Oct 23, 1-14(通讯作者,JCR Q2,IF=3.4)
2. Yanjing Zhu*, Ruiqi Huang*, Deheng Wang*, Liqun Yu, Yuchen Liu, Runzhi Huang, Shuai Yin, Xiaolie He, Bairu Chen, Zhibo Liu, Liming Cheng, Rongrong Zhu, EVs-mediated delivery of CB2 receptor agonist for Alzheimer's disease therapy, Asian Journal of Pharmaceutical Sciences, Volume 18, Issue 4,2023, 100835.(封面文章,共同一作,IF=10.2)
3. Zhongzhao Guo, Hong Ni, Zhengyu Cui, Zilu Zhu, Jiansheng Kang, Deheng Wang#, Zunji Ke#,Pain Sensitivity Related to Gamma Oscillation of Parvalbumin Interneuron in Primary Somatosensory Cortex in Dync1i1-/- Mice, Neurobiology of Disease, 2023, Volume 183, 106170, ISSN 0969-9961.(通讯作者,JCR Q1,IF=6.1)
4. Xiaojian Liao, Yuli Wu, Zi Wang, Deheng Wang, Hongmiao Zhang#, A Convolutional Spiking Neural Network with Adaptive Coding for Motor Imagery Classification, Neurocomputing, Volume 549, 7 September 2023, 126470.(IF=6)
5. Xiang Zou*, Zilu Zhu*, Yu Guo*, Hongmiao Zhang*, Yuchen Liu, Zhengyu Cui, Zunji Ke, Shize Jiang, Yusheng Tong, Zehan Wu, Ying Mao#, Liang Chen#, Deheng Wang#, Neural excitatory rebound induced by valproic acid may predict its inadequate control of seizures, eBioMedicine, 2022 Sep;83:104218.(通讯作者,IF=11.205)
6. Zhengyu Cui, Zhongzhao Guo, Luyao Wei, Xiang Zou, Zilu Zhu, Yuchen Liu, Jie Wang, Liang Chen, Deheng Wang#, Zunji Ke. (2022). Altered pain sensitivity in 5×FAD mice is associated with the dendritic spine loss in ACC pyramidal neurons. Pain, 2022;163(11):2138-2153.(封面文章,通讯作者,IF=7.926)
7. Da Song*, Deheng Wang*, Qinghu Yang*, Tianyi Yan*, Zhe Wang, Yan Yan, Juan Zhao, Zhen Xie, Yuchen Liu, Zunji Ke, Talal Jamil Qazi, Yanhui Li, Yili Wu, Qing Shi, Yiran Lang, Heao Zhang, Tao Huang, Chunjian Wang, Zhenzhen Quan#, Hong Qing#. The lateralization of left hippocampal CA3 during the retrieval of spatial working memory. Nature Communications, 2020, 11, 2901.(IF=14.919)
8. Ning Xue*, Deheng Wang*, Chunxiu Liu,Zunji Ke, Paz Elia, Tong Li, Cheng Chi, Yuhua Cheng, Jianhai Sun. A biodegradable porous silicon and polymeric hybrid probe for electrical neural signal recording. Sensors and Actuators B: Chemical, 2018, 272, 314-323(IF=6.393)
9. Deheng Wang, Stephanie Jacobs, Joe Z Tsien, Targeting the NMDA receptor subunit NR2B for treating or preventing age-related memory decline, Expert Opinion on Therapeutic Targets, 2014,18(10):1121-1130(IF=5.139)
10. Deheng Wang*, Zhenzhong Cui*, Qingwen Zeng, Hui Kuang, L.Phillip Wang, Joe Z.Tsien, Xiaohua Cao, Genetic Enhancement of Memory and Long-Term Potentiation but Not CA1 Long-Term Depression in NR2B Transgenic Rats, PLos One,2009,4(10).(IF=5.139)
11. Min H.Cho, Xiaohua Cao, Deheng Wang, Joe Z. Tsien, Dentate gyrus-specific manipulation of Ca2/calmodulin-dependent kinase II disrupts memory consolidation, PNAS, 2007, 104(41):16317-16322
12. 陈睿洲,朱子路,王德恒#,定痫丸对海人藻酸诱导的小鼠癫痫行为干预作用研究[J]. 长春中医药大学学报, 2023年04期, v.39, 389-394.
13. 卞跃峰,曹敏,王德恒#, 多通道在体记录技术发展现状及在中医药研究中的应用展望,上海中医药大学学报,2018,(1):92-97.
四、教学及教学奖励
1. 生理学(本科生)
2. Physiology(生理学,本科生,全英)
3. 医学电生理学(研究生)
4. 中西医结合基础研究方法和进展(研究生)
5. 2017年上海中医药大学基础医学院全英教学竞赛优胜奖
6. 2018年上海中医药大学第四届双语/全英教学竞赛三等奖
7. 2023年度上海中医药大学中西医结合学院中青年教师课堂教学竞赛二等奖
五、承担的科研项目
1. 国自然重大科研仪器研制项目:脑机接口超微柔性神经电极低侵袭植入微操作机器人系统,2022-2026,子课题负责人(主持134万)
2. 上海中医药大学中西医结合高原学科面上项目,A2-P1600320,黑质和纹状体多巴胺环路的神经编码研究,2016-2018,负责人(主持10万)
3. 上海中医药大学杏林学者,A1-U1820501040222,起止年限:2017-2020,负责人(主持15万)。
4. 上海高水平大学建设顶尖优势团队,A1-U18205010116,起止年限:2017-2022,参与。
5. 上海中医药大学预算内项目,恐惧等负性情绪记忆在杏仁核-海马-额叶环路的实时编码18LK002,起止年限:2018-2020,负责人(主持5万,结题)。