王炎，国家优青，医学博士，研究员，博士生导师、博士后合作导师

电子邮箱：wangyan_sg@126.com

办公电话：(021) 20256491

通讯地址（contact address）：上海市浦东新区张衡路528号曙光医院实验中心2楼203室

Yan Wang, Ph.D, Investigator, Doctoral supervisor and post doctoral cooperation supervisor

Email: wangyan_sg@126.com

TEL: (021) 20256491

Contact address: Room 203, 2/F, experimental center, Shuguang Hospital, 528 zhangheng Road, Pudong New District , Shanghai

学习和研究经历

• 2017.02-至今，副研究员，研究员，上海中医药大学附属曙光医院肿瘤研究所副所长

• 2013.09-2017.02，助理研究员，上海中医药大学附属龙华医院

• 2008.07-2013.09，研究实习员，助理研究员，上海中医药大学附属普陀医院

• 2011.09-2014.07，博士，上海中医药大学，中医内科学           

• 2005.09-2008.07，硕士，上海中医药大学，中西医结合临床  

• 2000.09-2005.07，学士，山东中医药大学，中医学

Education and Research Experience

• 2017.02-Present, Associate researcher fellow, Investigator, deputy director of Cancer Research Institute of Shuguang Hospital Affiliated to Shanghai University of traditional Chinese medicine

• 2013.09-2017.02, Assistant research fellow, associate research fellow, Longhua Hospital Affiliated to Shanghai University of traditional Chinese Medicine

• 2008.07-2013.09, Research probationer, assistant research fellow, Putuo Hospital Affiliated to Shanghai University of traditional Chinese medicine

• 2011.09-2014.07, Ph.D. Shanghai University of traditional Chinese medicine, internal medicine of traditional Chinese Medicine

• 2005.09-2008.07, Master, Shanghai University of traditional Chinese medicine, Clinical of integrated traditional Chinese and Western Medicine

• 2000.09-2005.07, Bachelor, Shandong University of traditional Chinese medicine, traditional Chinese Medicine

研究领域

• 情志理论的中医内涵研究

• 情志病的中医病因病机证治规律研究

• 情志应激促进肿瘤发生发展的机制

• 中医药调节情志应激抗肿瘤的作用机制研究

Research area

• Research on the Connotation of Emotion Theory in Traditional Chinese Medicine

• Study on the Law of Pathogenesis, Syndrome and Treatment of Emotional Diseases in Traditional Chinese Medicine

• The Mechanisms of Emotional Stress Promoting Tumor Development

• Study on the anti-tumor mechanisms of traditional Chinese medicine regulating emotional stress

主要社会团体任职

• 世界中医药联合会肿瘤精准医学专业委员会常务委员

• 上海市抗癌协会肿瘤营养支持与治疗专业委员会委员

• 中华中医药学会肿瘤分会青年委员

• 上海市中西医结合学会肿瘤分会委员

• 中国实验动物学会中医药分会委员

• 上海市中医药学会肿瘤分会委员

• 中国抗癌协会中西医整合肿瘤专业委员会常务委员

Employment of major social groups

• Standing member of tumor precision medicine professional committee of World Federation of traditional Chinese Medicine

• Member of tumor nutrition support and treatment professional committee of Shanghai anti cancer association

• Young member of cancer branch of Chinese society of traditional Chinese Medicine

• Member of cancer branch of Shanghai Society of integrated traditional Chinese and Western Medicine

• Member of Chinese medicine branch of Chinese society of experimental animals

• Member of cancer branch of Shanghai Society of traditional Chinese Medicine

• Standing member of tumor Professional Committee of integrated traditional Chinese and Western medicine of China Anti Cancer Association

研究成果及获奖

• 中西医结合治疗大肠癌的关键技术和推广应用，中国中西医结合科技奖二等奖，中华中医药学会

• 大肠癌血瘀证的生物学基础及效应机制，上海中西医结合科学技术奖三等奖，上海市中西医结合学会

• 健脾解毒法防治大肠癌术后转移的临床应用和基础研究 科学技术进步奖二等奖，中华人民共和国教育部专利

• 上海市青年拔尖人才，上海市科学技术委员会

• 上海市青年科技启明星，上海市科学技术委员会

• 上海市“新百人”，上海市卫生健康委员会

• 上海市医树奖，上海市女医师协会

Achievements and Awards

• Key technology and popularization of integrated traditional Chinese and Western medicine in the treatment of colorectal cancer, Second prize of China Science and Technology Award for integrated traditional Chinese and Western Medicine, Chinese society of traditional Chinese Medicine

• Biological basis and mechanisms of blood stasis syndrome in colorectal cancer, Third prize of Shanghai Science and Technology Award for integrated traditional Chinese and Western Medicine, Shanghai Society of integrated traditional Chinese and Western Medicine

• Clinical application and basic study of strengthening spleen and detoxification in the prevention and treatment of postoperative metastasis of colorectal cancer, Second prize of science and Technology Progress Award, Patent of the Ministry of education of the people's Republic of China

• Shanghai top talent, Shanghai Science and Technology Commission

• Shanghai Excellence in Medicine Award for Women, Shanghai Women Doctors Association

基金支持及参与（Grant Funding）

• 主持国家自然科学基金5项，省部级课题多项

1. 国家自然科学基金青年项目：丹参酮ⅡA聚乳酸纳米粒介导FN/integrinα5β1抗肝癌侵袭转移的研究（81001594），2011.01-2013.12，获20万资助，结题，主持。

2. 国家自然科学基金面上项目：EpCAM-丹参酮ⅡA纳米粒靶向肝癌干细胞调控Wnt/β-catenin信号通路抗肝癌侵袭转移的机制研究（81573764），2016.01-2019.12，获74.4万资助，结题，主持。

3. 国家自然科学基金面上项目：外泌体通过Fz受体激活β-catenin/TCF信号通路促进大肠癌转移机制及丹参酮ⅡA纳米分子靶向作用（81774095），2018.01-2021.12，获55万资助，在研，主持。

4. 国家自然科学基金面上项目：小柴胡汤通过肠道菌群介导NF-κB/NLRP3信号通路调节大肠癌转移压力应激性的机制（82074232），2021.01-2024.1，获55万资助，在研，主持。

5. 国家自然科学基金优秀青年科学基金：中西医结合肿瘤学（82122075），2022.01-2024.12，获200万资助，在研，主持。

6. 上海市科学技术委员会：经方调节肠道微生态防治大肠腺瘤的临床研究（19401972200），2019.09-2022.06，获50万资助，在研，主持。

Grant Funding

Granted 5 National Natural Science Foundation of China (NSFC) funds as PI and a number of provincial and ministerial projects