中西医结合学院

School of Integrative Medicine.

贾丰菁 助理研究员

发布者:中西医发布时间:2021-08-25浏览次数:451




贾丰菁,助理研究员,

电子邮箱(Email):jiafengjing@shutcm.edu.cn 

办公室电话(TEL):(021) 5132-2266

通讯地址(contact address):浦东新区蔡伦路1200号创新科技楼4B407

(B407, 4/F, Innovation and Technology Building, 1200 Cailun Rd, Pudong, Shanghai)

 

研究领域(Research area

w  中药抗肿瘤药理

Pharmacology and Antitumor Activity of Traditional Chinese medicine

w  多肽生物活性及作用机制

     The bioactivity and the mechanism of peptides

 

 

基金支持及参与(Grant Funding

w  主持国家自然科学基金1

 国自然青年基金:抗菌肽Jelleine-ICRISPRa技术联用靶向目标病原菌的抗菌作用研究(82003641),2021.01-2023.12,获24万资助,在研,主持。

 

Grant Funding

w  Granted 1 National Natural Science Foundation of China (NSFC) funds as PI

 

论文发表(Publication

w  Jia F, Wang J, Zhang L, Zhou J, He, et al. Multiple action mechanism and in vivo antimicrobial efficacy of antimicrobial peptide Jelleine-I. J Pept Sci. 2021. 27(3): e3294. 

w  Jia F, Liang X, Wang, et al. Tryptic Stability and Antimicrobial Activity of the Derivatives of Polybia-CP with Fine-Tuning Modification in the Side Chain of Lysine. Int J Pept Res Ther. 2021.27(2):1-12.

w  Jia F, Li X, Zhang C, Tang X. The expanded development and application of CRISPR system for sensitive nucleotide detection. 2020. Protein Cell. 11(9): 624-629.

w  Jia F, Zhang Y, Wang J, Peng J, Zhao P, Zhang L, Yao H, Ni J, Wang K. The effect of halogenation on the antimicrobial activity, antibiofilm activity, cytotoxicity and proteolytic stability of the antimicrobial peptide Jelleine-I. Peptides. 2019.112: 56-66.

w  Jia F, Wang J, Peng J, Zhao P, Kong Z, Wang, et al. The in vitro, in vivo antifungal activity and the action mode of Jelleine-I against Candida species. Amino Acids. 2018. 50(2) :229-239. 

w  Jia F, Wang J, Peng J, et al. D-amino acid substitution enhances the stability of antimicrobial peptide polybia-CP. Acta Biochim Biophys Sin, 2017, 49(010):916-925.

w  Wang K#, Jia F#, Dang W, et al. Antifungal effect and action mechanism of antimicrobial peptide polybia-CP. J Pept Sci, 2016, 22(1):28-35.