赵玲 副研究员
赵玲，副研究员，硕士生导师
电子邮箱：lzhao@shutcm.edu.cn
办公室电话：(021) 5132-2266
通讯地址：浦东新区蔡伦路1200号创新科技楼4楼B407
Ling Zhao, Associate research fellow, Master tutor
Email: lzhao@shutcm.edu.cn
TEL: (021) 5132-2266
Contact address: B407, 4/F, Innovation and Technology Building, 1200 Cailun Rd, Pudong, Shanghai
学习和研究经历
w 2020.07-至今, 副研究员，上海中医药大学，中西医结合研究院
w 2018.11-2020.6，博士后，香港浸会大学，香港中医药临床研究中心
w 2014.09-2018.11，博士研究生，香港浸会大学，中医药学院
w 2013.08-2014.08，高级研究助理，香港浸会大学，中医药学院
w 2009.09-2012.06，硕士研究生，吉林农业大学，中药材学院
w 2005.09-2009.07，本科，吉林农业大学，中药材学院
Education and Research Experience
w 2020.07- Present, Associate research fellow, Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine
w 2018.11-2020.6, Postdoc Fellow, Hong Kong Chinese Medicine Clinical Study Center, Hong Kong Baptist University
w 2014.09-2018.11, Ph.D. program, School of Traditional Chinese Medicine, Hong Kong Baptist University
w 2013.08-2014.08, Senior Research Assistant, School of Traditional Chinese Medicine, Hong Kong Baptist University
w 2009.09-2012.06, M.M. program, College of Chinese Medicine, Jilin Agricultural University
w 2005.09-2009.07, B.Sc program, College of Chinese Medicine, Jilin Agricultural University
研究领域
w 肠道微生物的生理及代谢功能
w 基于肠道微生物的消化道疾病机制
w 肠道微生物相关中医药药理机制
Research area
w Physiological and metabolic functions of the gut microbiota
w Gut microbiota-driven mechanism underlying gastrointestinal diseases
w Gut microbiota-involved pharmacology of Traditional Chinese Medicine
基金支持及参与（Grant Funding）
w 主持与参与国家自然科学基金3项
1. 国自然青年基金：胆汁酸转化梭菌通过5-羟色胺通路加剧肠易激综合征腹泻症状的机制研究（82000504），2021.01-2023.12，获24万资助，在研，主持；
2. 国自然面上基金：中药复方JCM-16021促进肠道菌群的短链脂肪酸生产改善肠屏障功能的机制研究（81973538），2020.01-2023.12，获55万资助，在研，参加；
3. 国自然青年基金：MT1-MMP调控肿瘤相关巨噬细胞促淋巴管生成的机制（81802838），2019.01-2021.12，获22万资助，在研，参加；
w 2020年获上海中医药大学“青年杏林学者”培养计划资助
w 2021年“中西医结合防治肿瘤临床与基础研究”上海市教委专项拨款
Grant Funding
w Granted 3 National Natural Science Foundation of China (NSFC) funds as PI or Co-PI
w Young Xinglin scientists Program funded by Shanghai University of Traditional Chinese Medicine (2020)
w Shanghai Municipal Education Commission special grant for Clinical and basic research on the prevention and treatment of cancers with integrative medicine (2021)
论文发表（Publication）
w LJ Han#, L Zhao#, Y Zhou#, C Yang#, T Xiong#, L Lu#, YS Deng, W Luo, Y Chen, QW Qiu, XX Shang, ZC Mo, SG Huang, SP Huang, Z Liu, W Yang, LX Zhai, ZW Ning, CY Lin, T Huang, CW Cheng, LLD Zhong, SC Li, ZX Bian, XD Fang. Altered metabolome and microbiome features provide clues in understanding irritable bowel syndrome and depression comorbidity. ISME J (IF=10.3, accepted).
w SY Shao#, R Jia#, L Zhao#, YR Zhang, YF Guan, HT Wen, JW Liu, YY Zhao, Y Feng, ZZ Zhang, Q Ji, Q Li, Y Wang. Xiao-Chai-Hu-Tang ameliorates tumor growth in cancer comorbid depressive symptoms via modulating gut microbiota-mediated TLR4/MyD88/NF-κB signaling pathway. Phytomedicine (IF=5.3), 2021,153606.
w L Zhao, W Yang, Y Chen, FJ Huang, L Lu, CY Lin, T Huang, ZW Ning, LX Zhai, LLD. Zhong, WC Lam, Z Yang, X Zhang, CW Cheng, LJ Han, QW Qiu, XX Shang, RY Huang, HT Xiao, ZX Ren, DF Chen, SL Sun, H El-Nezami, ZW Cai, AP Lu, XD Fang, W Jia, ZX Bian. A Clostridia-rich microbiota enhances bile acid excretion in diarrhea-predominant irritable bowel syndrome. J Clin Invest (IF=14.8) 2020 Jan 2; 130(1): 438–450.
w ML Wei#, FJ Huang#, L Zhao#, YJ Zhang, W Yang, SL Wang, MC Li, XL Han, K Ge, C Qu, C Rajani, GX Xie, XJ Zheng, AH Zhao, ZX Bian, W Jia. EBioMedicine(IF=8.1) 2020 May; 55: 102766.
w L Zhao, XD Fang, W Jia, ZX Bian, Managing Chronic Diarrhea From a Gut Microbiota-Bile Acid Perspective. Clin Transl Gastroenterol (IF=4.8) 2020 Aug; 11(8): e00208.
w T Huang#, L Zhao#, CY Lin, L Lu, ZW Ning, DD Hu, LLD Zhong, ZJ Yang, ZX Bian. Chinese Herbal Medicine (MaZiRenWan) Improves Bowel Movement in Functional Constipation Through Down-Regulating Oleamide. Front Pharmacol (IF=5.8) 2019; 10: 1570.
w L Zhao, YF Huang, L Lu, W Yang, T Huang, ZS Lin, CY Lin, HY Kwan, HLX Wong, Y Chen, SL Sun, XF Xie, XD Fang, HM Yang, J Wang, LX Zhu, ZX Bian. Saturated long-chain fatty acid-producing bacteria contribute to enhanced colonic motility in rats. Microbiome(IF=13.6)2018 Jun 14;6(1):107.
w CY Lin#, L Zhao#, T Huang, Lin Lu, Mahjabin Khan, Jie Liu, LLD Zhong, ZW Cai, BM Fan, AOL Wong, ZX Bian. Spexin acts as novel regulator for bile acid synthesis. Front Physiol. (IF=4.1)2018; 9: 378.